App Detects Abnormal Vital signs

Dr. Jaques Reifman, Director, Biotechnology High Performance Computing Software Applications Institute (BHSAI) at the Telemedicine & Advanced technology Research Center (TATRC), at Ft Detrick, realizes that early detection of exposure to pathogens from biological weapons or emerging infectious diseases is critical for maintaining military and population health.

The TATRC team developed the 2B-Healthy app to use for automated real time detection of abnormal vital signs. A malaria infection challenge was chosen to study because it has established clinical signs to detect automated real time model with a well- defined time course and symptoms of infection, direct clinical and military relevance, a long incubation period that allows time to make predictions, and early and late stage diagnostic tests approved by FDA.

This study used wearable technology such as a Samsung Gear  S3 smartwatch to collect continuous vital sign data from volunteers, and the data wirelessly was transmitted to the Samsung Galaxy S8 smartphone.

Consisting of commercial-off-the-shelf  hardware and customized software, the 2B-Healthy app pairs a non-invasive wearable device that continuously collects vital sign data with a proprietary algorithm to identify physiological changes associated with abnormal events including infections.

The successful development of the 2B-Healthy app enables the U.S military to carry out automated rapid detection for service member infections including SARS-CoV-2 infected individuals before they can infect others. This is essential to maintaining readiness during the current pandemic as well as future ones.

Information for the article 2B-Healthy: BHSAI’s AI System for Early Warning of Adverse Conditions in Humans appeared in the July 2021 issue of TATRC Times. For more information on this project, contact Dr. Jaques Reifman, at



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