Foundation Issues RFP

Current methods for drug discovery have had limited success at predicting clinical efficacy of investigational therapies in patients with Alzheimer’s disease and other age-related dementias. The use of computational modeling, systems biology and pharmacology, and translational bioinformatics represents a relatively under developed opportunity to study age-related dementias.

The Alzheimer’s Drug Discovery Foundation (ADDF) program on Aging & Alzheimer’s Disease Prevention has issued a Request for Proposal (RFP) with up to $150,000 available seeking innovative computational approaches to map disease and predict the efficacy of drugs to treat and prevent dementia.

A variety of approaches and outcomes will be considered. Priority will be given to interdisciplinary teams composed of computational and biology disease experts and to proposals that use and may develop open-access databases of biological and clinical data.

Both non-profit academic research centers and for-profit biotechnology companies are eligible to apply. Each grant is for one year duration with the possibility of follow-on funding for computational or experimental research.

The deadline for applications for the proposal “Creative Computational Approaches to Accelerate Drug Discovery for the Treatment and Prevention of Dementia” is September 5, 2013 with the award to be announced in spring 2014. . Submission of a Letter of Intent is required prior to August 22, 2013.  All Letters of Intent must be submitted electronically at

Go to for more information. For more details, email Niyati Thakker, Grants Manager at or phone 212-901-8019.

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