The Patient-Centered Outcomes Research Institute (PCORI) https://www.pcori.org intends to release a Targeted PCORI Funding Announcement (PFA on September 7, 2022 seeking to fund high quality comparative clinical effectiveness research projects.
Funds will be available for up to $50 million with total direct costs up to $10 million. The plan is to focus on different approaches to incorporating access to and use of telehealth to optimize management of multiple chronic conditions in primary care, particularly among vulnerable populations.
This pre-announcement has been provided to allow potential applicants additional time to identify collaborators, obtain stakeholder input on potential studies, and develop responsive high quality proposals.
With the rapid expansion of telehealth modalities for remote care delivery during the COVID-19 pandemic, a clear need has emerged to identify the most effective, evidence-based ways to incorporate telehealth as part of routine clinical workflow. The plan is to facilitate optimal chronic disease management beyond the pandemic specifically among individuals with multiple chronic conditions in primary care settings.
The PCORI Funding Announcement is soliciting applications that respond to the following question:
- What is the comparative clinical effectiveness of different approaches to incorporating access to and use of telehealth to optimize management of multiple chronic conditions in primary care, particularly among vulnerable populations?
Although, the focus should be primary care, studies can incorporate home-based care and include specialty care as appropriate. Applicants can propose multisite individual, or cluster randomized clinical trials, or natural experiments.
Applicants are also encouraged to:
- Conduct analyses to evaluate the relative clinical effectiveness by the appropriate telehealth modality
- To include periodic outcome assessments with follow-up for at least 12 months
- Propose well justified outcomes that are clinically meaningful, considered important by patients, and can be impacted by interventions evaluated in CER studies for a maximum duration of 5 years.
Online system opens on September 7, 2022, and on September 15, 2022, 12:00 to 1:00 ET a Applicant Town Hall will be available for viewing. The Letter of Intent is due October 4, 2022 with the Application deadline to be January 2023. Merit review is March 2023 and awards will be announced July 2023, with the earliest start date scheduled to be November 2023.